Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635642 | 1.00 | GBA2 (0.44) | GBA2POLBLMNASMN1; SMN2IDH1 | |
| SCHEMBL28819356 | 0.89 | ALDH1A1 (0.48) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6819743 | 0.89 | ALDH1A1 (0.48) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10084211 | 0.89 | ALDH1A1 (0.48) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL16758164 | 0.89 | ALDH1A1 (0.48) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10292032 | 0.86 | ATM (0.53) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20558080 | 0.86 | ATM (0.53) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL31728231 | 0.86 | ATM (0.53) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3663153 | 0.86 | ATM (0.53) | GBA2POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10084437 | 0.86 | ATM (0.53) | GBA2POLBLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493506-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1992-07-08 | — | — | EP | disclosed |
| WO-1991004247-A1 | CHIMERIC AMINO ACIDS AND PEPTIDES CONTAINING THESE ANALOGUES | GENENTECH, INC. (US) | 1991-04-04 | — | — | WO | disclosed |