SCHEMBL9635649

SCHEMBL9635649

O=C(O)C1=C(C(=O)O)C(C(=O)O)=C1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.40
CA2 P00918 5/20 0.40
TSHR P16473 4/20 0.40
CA9 Q16790 4/20 0.40
TP53 P04637 1/20 0.40
ALOX15 P16050 3/20 0.35
CYP1A2 P05177 2/20 0.35
DAO P14920 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SRD5A2 P31213 1/20 0.33
ACHE P22303 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
DPP4 P27487 1/20 0.32
CA12 O43570 3/20 0.32
CA7 P43166 3/20 0.32
CA14 Q9ULX7 3/20 0.32
CA3 P07451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1290379 0.77 FGFR1 (0.37) CA1CA2TSHRCA9TP53
SCHEMBL15881020 0.74 TP53 (0.32) TSHRTP53
SCHEMBL9063070 0.74 ALDH1A1 (0.36) TSHRTP53DAOALDH1A1SRD5A2
Mellitic Acid SCHEMBL23507 0.67 CYP1A2 (0.50) CA1CA2TSHRCA9TP53
Mellitic Acid SCHEMBL22971 0.67 CYP1A2 (0.50) CA1CA2TSHRCA9TP53
Mellitic Acid SCHEMBL29638026 0.63 CYP1A2 (0.47) CA1CA2TSHRCA9TP53
SCHEMBL1647075 0.63
SCHEMBL133822 0.63
Bicarbonate SCHEMBL6478072 0.60 CA1 (1.00) CA1CA2TSHRCA9TP53
Bicarbonate SCHEMBL1179 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5111318-A FERROELECTRIC LIQUID CRYSTAL ELEMENT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-05-05 US disclosed
EP-0368204-A2 Ferroelectric liquid crystal element NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-05-16 EP disclosed