Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637090 | 0.88 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2ABCC4ABCB11PGR | |
| SCHEMBL9635475 | 0.87 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ABCC4ABCB11PGR | |
| SCHEMBL9757070 | 0.86 | CYSLTR1 (0.44) | CYSLTR1KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL9635790 | 0.79 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2 | |
| SCHEMBL9318797 | 0.76 | CYSLTR2 (0.48) | CYSLTR1GPR35CYSLTR2TP53 | |
| SCHEMBL6961638 | 0.76 | GPR35 (0.59) | CYSLTR1GPR35CYSLTR2ABCC4ABCB11 | |
| SCHEMBL5355934 | 0.76 | CYSLTR2 (0.56) | CYSLTR1GPR35CYSLTR2ABCC4ABCB11 | |
| SCHEMBL9760136 | 0.74 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2KDM4EMEN1NPC1 | |
| SCHEMBL10870251 | 0.74 | CYSLTR2 (0.61) | CYSLTR1GPR35CYSLTR2ABCC4ABCB11 | |
| SCHEMBL9757169 | 0.73 | GPBAR1 (0.48) | CYSLTR1KDM4EMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A4 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1992-01-08 | — | — | EP | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |