Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 16/20 | 0.70 |
| ▸ | PDE4A | P27815 | 9/20 | 0.70 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.70 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.70 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636127 | 0.87 | PDE5A (0.68) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9636233 | 0.86 | PDE2A (0.61) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9635028 | 0.85 | PDE5A (0.72) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9635758 | 0.81 | PDE2A (0.73) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9635750 | 0.80 | PDE5A (0.61) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9634782 | 0.80 | PDE2A (0.53) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9634703 | 0.80 | PDE5A (0.57) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11771266 | 0.79 | PDE5A (1.00) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9636272 | 0.79 | PDE5A (0.70) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9635759 | 0.79 | PDE5A (0.70) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104881-A | 2-ARYLIMIDAZOPYRIDINES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-04-14 | — | — | US | disclosed |
| US-4616090-A | 2-arylimidazopyridines intermediates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0072926-A1 | 2-Arylimidazopyridines | MERCK PATENT GmbH (DE) | 1983-03-02 | — | — | EP | disclosed |