Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 11/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536908 | 0.83 | ALDH1A1 (0.63) | TYK2ALDH1A1L3MBTL1RORCCYP2C9 | |
| SCHEMBL18713609 | 0.83 | TYK2 (0.55) | TYK2ALDH1A1L3MBTL1RORCCYP2C9 | |
| SCHEMBL784920 | 0.83 | TYK2 (0.55) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL29932942 | 0.81 | TYK2 (0.54) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL9525419 | 0.81 | TYK2 (0.54) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL5463408 | 0.81 | TYK2 (0.54) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL2092585 | 0.80 | ALDH1A1 (0.61) | TYK2ALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL25049814 | 0.79 | TYK2 (0.48) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL18671762 | 0.79 | TYK2 (0.51) | TYK2ALDH1A1RORCCYP2C9CYP3A4 | |
| SCHEMBL19648388 | 0.77 | TYK2 (0.61) | TYK2ALDH1A1L3MBTL1RORCCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365914-B1 | FLUORINE-CONTAINING ACETOPHENONES OPTIONALLY HALOGENATED IN THE CH3-GROUP, AND THEIR PREPARATION FROM FLUORINATED BENZONITRILES | BAYER AG (DE) | 1992-07-22 | — | — | EP | claimed |