Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 14/20 | 0.61 |
| ▸ | GABRD | O14764 | 14/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 14/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 14/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 14/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 14/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.61 |
| ▸ | GABRA4 | P48169 | 14/20 | 0.61 |
| ▸ | GABRE | P78334 | 14/20 | 0.61 |
| ▸ | GABRA6 | Q16445 | 14/20 | 0.61 |
| ▸ | GABRG1 | Q8N1C3 | 14/20 | 0.61 |
| ▸ | GABRG3 | Q99928 | 14/20 | 0.61 |
| ▸ | GABRQ | Q9UN88 | 14/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637775 | 1.00 | GABRP (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9637571 | 0.93 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9637562 | 0.93 | GABRP (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636612 | 0.77 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636543 | 0.77 | GABRP (0.64) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8950548 | 0.76 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10431279 | 0.74 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636567 | 0.73 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9636585 | 0.73 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9637681 | 0.72 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372816-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-07-29 | — | — | EP | claimed |
| WO-1990006304-A1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-14 | — | — | WO | claimed |
| EP-0372816-A1 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-13 | — | — | EP | claimed |
| EP-0372816-B1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-07-29 | — | — | EP | disclosed |
| WO-1990006304-A1 | NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-14 | — | — | WO | disclosed |
| EP-0372816-A1 | Novel heterocyclic pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-06-13 | — | — | EP | disclosed |