Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636225 | 0.95 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL9636408 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL9636176 | 0.94 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL9634926 | 0.94 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL9669421 | 0.93 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL9636155 | 0.93 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL8434112 | 0.90 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL10647454 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL10863653 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 | |
| SCHEMBL8435505 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337231-B1 | I. M. INJECTION FORMS OF GYRASE-INHIBITORS | BAYER AG (DE) | 1992-06-17 | — | — | EP | disclosed |
| EP-0337231-A2 | I. M. injection forms of gyrase-inhibitors | BAYER AG (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0167763-A1 | 7-Amino-1-cyclopropyl-6,8-dihalo-1,4-dihydro-4-oxo-3-quinoline-carboxylic acids, process for their preparation and bactericidal agents containing them | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0164619-A1 | 2,4,5-Trihalo or 2,3,4,5-tetrahalo benzene derivatives and process for producing them | BAYER AG (DE) | 1985-12-18 | — | — | EP | disclosed |