Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 11/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26653947 | 0.78 | PARP10 (0.54) | RYR2MAPKAPK2PARP10PARP11MEN1 | |
| SCHEMBL30657972 | 0.78 | PARP10 (0.54) | RYR2MAPKAPK2PARP10PARP11MEN1 | |
| SCHEMBL14691900 | 0.78 | PARP10 (0.50) | RYR2GRM5PARP10PARP11MEN1 | |
| SCHEMBL26942243 | 0.78 | PARP10 (0.54) | RYR2GRM5MAPKAPK2PARP10PARP11 | |
| SCHEMBL1238521 | 0.78 | PRKD1 (0.50) | RYR2MAPKAPK2PARP10PARP11MEN1 | |
| SCHEMBL9635151 | 0.78 | PARP10 (0.50) | RYR2GRM5PARP10PARP11MEN1 | |
| SCHEMBL10363630 | 0.78 | KDM4E (0.54) | GRM5HDAC4HDAC1HDAC7HDAC8 | |
| SCHEMBL5956797 | 0.75 | KDM4E (0.44) | GRM5HDAC4HDAC1HDAC7HDAC8 | |
| SCHEMBL9635297 | 0.75 | PARP1 (0.55) | RYR2MAPKAPK2PARP10PARP11MEN1 | |
| SCHEMBL14691928 | 0.74 | RYR2 (0.78) | RYR2GRM5MAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368063-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-4990707-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |