Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637155 | 1.00 | MMP2 (0.47) | MMP2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL9636709 | 1.00 | MMP2 (0.47) | MMP2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL9637159 | 1.00 | MMP2 (0.47) | MMP2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL30799335 | 0.85 | MMP2 (0.55) | MMP2OPRM1OPRD1OPRK1BACE1 | |
| SCHEMBL9636717 | 0.85 | MMP2 (0.47) | MMP2OPRM1OPRD1OPRK1F2 | |
| SCHEMBL9637291 | 0.85 | DPP8 (0.46) | — | |
| SCHEMBL9637284 | 0.85 | DPP8 (0.46) | — | |
| SCHEMBL2184328 | 0.84 | MME (0.47) | BACE1MMEACECPA1ACE2 | |
| SCHEMBL9638023 | 0.84 | CTSC (0.50) | OPRM1OPRD1OPRK1MMEACE | |
| SCHEMBL9638027 | 0.84 | CTSC (0.50) | OPRM1OPRD1OPRK1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4892939-A | ANTITUMOR, ANTIVIRAL AND IMMUNOSUPRESSIVE AGENTS | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-09 | — | — | US | claimed |