Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946615 | 0.81 | CYP2D6 (0.48) | CYP2D6LMNAALDH1A1KMT2AADRA2A | |
| SCHEMBL2318477 | 0.81 | CYP2D6 (0.45) | CYP2D6HPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21854831 | 0.78 | LMNA (0.49) | CYP2D6LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL30300820 | 0.78 | LMNA (0.49) | CYP2D6LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL8283809 | 0.77 | CYP2D6 (0.56) | CYP2D6HPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2163297 | 0.76 | HPGD (0.47) | CYP2D6HPGDLMNAALDH1A1ADRA2A | |
| SCHEMBL2369710 | 0.76 | CYP2D6 (0.43) | CYP2D6LMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3250856 | 0.74 | CYP2D6 (0.46) | CYP2D6LMNAALDH1A1KMT2AADRA2A | |
| SCHEMBL10582816 | 0.74 | CYP2D6 (0.46) | CYP2D6LMNAALDH1A1KMT2AADRA2A | |
| SCHEMBL5158960 | 0.74 | CYP2D6 (0.73) | CYP2D6LMNAKMT2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294557-B1 | PROCESS FOR THE PREPARATION OF 3-PHENYL-2-METHYLPROPANOL AND ITS PARA-SUBSTITUTED ALKYLIC DERIVATIVES | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-07-08 | — | — | EP | disclosed |