Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447606 | 0.84 | PARP1 (0.44) | PARP1PARP10ACHEITGB3ITGA2B | |
| SCHEMBL11725306 | 0.74 | METAP1 (0.51) | ACHE | |
| Hydrochloric Acid SCHEMBL11728965 | 0.73 | METAP1 (0.53) | ACHE | |
| SCHEMBL9635389 | 0.72 | SLC6A4 (0.44) | SLC6A4KDM1ADRD2HTR2ABRD3 | |
| SCHEMBL9180622 | 0.69 | ACHE (0.51) | PARP1PARP10ACHEDRD2HTR2A | |
| SCHEMBL4843083 | 0.69 | METAP1 (0.58) | ACHECHRM2CHRM1HTR2A | |
| SCHEMBL12306069 | 0.69 | ACHE (0.44) | ACHECHRM2CHRM1 | |
| SCHEMBL30861080 | 0.68 | ACHE (0.68) | ACHE | |
| SCHEMBL5435617 | 0.68 | ACHE (0.68) | ACHE | |
| SCHEMBL448182 | 0.68 | ACHE (0.46) | ACHECHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |