SCHEMBL9636971

SCHEMBL9636971

OC(O)(c1ccccc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.58
KIF11 P52732 3/20 0.54
PTPN5 P54829 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.43
CYP17A1 P05093 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MGLL Q99685 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP1A2 P05177 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25489530 0.97 CYP2C9 (0.60) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL161069 0.86 CYP2C19 (0.50) CYP2C9ALDH1A1CYP3A4MAPK1CYP1A2
SCHEMBL2858210 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL812743 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL813153 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL8164004 0.83 CYP2C19 (0.48) CYP2C9ALDH1A1CYP3A4MAPK1CYP1A2
Hydrochloric Acid SCHEMBL28294820 0.83 CYP2C19 (0.48) CYP2C9ALDH1A1CYP3A4MAPK1CYP1A2
SCHEMBL21842336 0.81 CYP2C9 (0.54) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL31589360 0.81 CYP2C9 (0.60) CYP2C9KIF11PTPN5MMP3BCL2L1
SCHEMBL18639619 0.80 CYP2C9 (0.54) CYP2C9KIF11PTPN5MMP3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0177713-B2 POLYCARBONATE AND OPTICAL DISC SUBSTRATE MITSUBISHI KASEI CORPORATION (JP) 1992-06-10 EP claimed
EP-0177713-B1 POLYCARBONATE AND OPTICAL DISC SUBSTRATE MITSUBISHI KASEI CORPORATION (JP) 1989-05-31 EP claimed