SCHEMBL2858210

SCHEMBL2858210

OC(c1ccccc1)(c1ccccc1)C(O)(c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.58
KIF11 P52732 3/20 0.54
PTPN5 P54829 1/20 0.48
CYP1A2 P05177 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
ALDH1A1 P00352 2/20 0.47
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MGLL Q99685 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
PTPN1 P18031 1/20 0.41
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858670 0.86 CYP2C9 (0.50) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL36629 0.86 CYP1A2 (0.48) CYP2C9CYP1A2ALDH1A1MAPK1CYP3A4
SCHEMBL7173455 0.86 CYP1A2 (0.48) CYP2C9CYP1A2ALDH1A1MAPK1CYP3A4
SCHEMBL812743 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL813153 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL9636971 0.84 CYP2C9 (0.58) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL25489530 0.81 CYP2C9 (0.60) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL31589360 0.81 CYP2C9 (0.60) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL21842336 0.81 CYP2C9 (0.54) CYP2C9KIF11PTPN5CYP1A2MMP3
SCHEMBL18639619 0.80 CYP2C9 (0.54) CYP2C9KIF11PTPN5MMP3BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3597441-B1 METHOD OF PRODUCING A MULTILAYERED PRODUCT TRIP LICENSES BV (NL) 2021-04-28 EP disclosed
EP-3449315-B1 RADIATION CURABLE DRY TONER AND METHOD FOR PREPARING THE SAME XEIKON MFG NV (BE) 2021-03-31 EP disclosed
US-10919288-B2 Method of producing a multilayered product PROCRAFT DEVELOPMENT BV (NL) 2021-02-16 US disclosed
EP-3510058-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME The University of Massachusetts (US) 2019-07-17 EP disclosed
US-20190202953-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS 2019-07-04 US disclosed
US-20190129322-A1 Radiation Curable Dry Toner and Method for Preparing the Same XEIKON MANUFACTURING N.V. (BE) 2019-05-02 US disclosed
WO-2018039325-A1 POLYMERIZING COMPOSITION, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME THE UNIVERSITY OF MASSACHUSETTS (US) 2018-03-01 WO disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
US-4443495-A ETHYLENICALLY UNSATURATED COMPOUND AND A POLYTHIOL, SCREEN PRINTABLE W. R. GRACE & CO. (US) 1984-04-17 US disclosed
US-4406826-A POLYTHIOL, UNSATURATED MONOMER, METAL W. R. GRACE & CO. (US) 1983-09-27 US disclosed
US-4374963-A Heat curable epoxy-acrylate compositions W. R. GRACE & CO. (US) 1983-02-22 US disclosed
US-4352723-A ULTRAVIOLET RADIATION; PHOTOINITIATOR AND AROMATIC PINACOL W. R. GRACE & CO. (US) 1982-10-05 US disclosed
US-4288527-A Dual UV/thermally curable acrylate compositions with pinacol W. R. GRACE & CO. (US) 1981-09-08 US disclosed
US-4132812-A FREE RADICAL INITIATOR W. R. GRACE & CO. (US) 1979-01-02 US disclosed
US-4117196-A PHOTOCURABLE IMIDIZABLE POLYENE-POLYTHIOL COMPOSITIONS W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4117017-A PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR W. R. GRACE & CO. (US) 1978-09-26 US disclosed
US-4080484-A POLYAMIDE-ACID OR POLYIMIDE W. R. GRACE & CO. (US) 1978-03-21 US disclosed
US-4020233-A Heat activated ethylenically unsaturated-polythiol compositions W. R. GRACE & CO. (US) 1977-04-26 US disclosed