Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636904 | 0.86 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1MAOBALOX5 | |
| SCHEMBL9635505 | 0.85 | CYSLTR1 (0.48) | CYSLTR1GPBAR1 | |
| SCHEMBL9635545 | 0.83 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9636896 | 0.82 | ALOX5 (0.48) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9757063 | 0.81 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1ALOX5APPDE10A | |
| SCHEMBL9635506 | 0.81 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9635494 | 0.81 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9635564 | 0.79 | CYSLTR1 (0.47) | CYSLTR1GPBAR1 | |
| SCHEMBL9636900 | 0.79 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9635568 | 0.79 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A4 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1992-01-08 | — | — | EP | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |