Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 15/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637076 | 1.00 | ADORA2B (0.61) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9637193 | 0.96 | ADORA2B (0.63) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9637190 | 0.96 | ADORA2B (0.63) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9155023 | 0.95 | ADORA2B (0.65) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9155034 | 0.95 | ADORA2B (0.65) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9155681 | 0.92 | ADORA2B (0.64) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9155692 | 0.92 | ADORA2B (0.64) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9157123 | 0.91 | ADORA2B (0.65) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL9157110 | 0.91 | ADORA2B (0.65) | ADORA2BADORA3ADORA1ADORA2AKDM4E | |
| SCHEMBL6554070 | 0.91 | ADORA2B (0.72) | ADORA2BADORA3ADORA1ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243192-B1 | ANTIVIRAL 8-PHENYLXANTHINES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-07-15 | — | — | EP | disclosed |
| US-5015647-A | Using Purine Cinnamic Acid Compounds | BURROUGHS WELLCOME CO. (US) | 1991-05-14 | — | — | US | disclosed |