Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | HTR2B | P41595 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366282 | 0.80 | — | — | |
| SCHEMBL15255464 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL18772710 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL9880267 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL27163373 | 0.72 | GAA (0.41) | ALDH1A1GAAHPGDHSD17B10LMNA | |
| SCHEMBL10436985 | 0.72 | ALDH1A1 (0.49) | ALDH1A1GAAHPGDHSD17B10KDM4E | |
| SCHEMBL18772790 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL18722400 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL2616363 | 0.71 | ALDH1A1 (0.44) | ALDH1A1GAAHPGDHSD17B10HTR2A | |
| SCHEMBL9680501 | 0.69 | CDA (0.37) | ALDH1A1GAAHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130319-A | Cognition activators for memory disorders | I.S.F. SOCIETA PER AZIONI (IT) | 1992-07-14 | — | — | US | disclosed |