Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671969 | 0.91 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29445387 | 0.91 | CA12 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL517538 | 0.86 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18797222 | 0.84 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28803912 | 0.82 | SLC6A4 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9815483 | 0.82 | CA1 (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10772207 | 0.81 | CA1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8802402 | 0.81 | NPSR1 (0.47) | POLBPKMCYP1A2CYP2C19LMNA | |
| SCHEMBL8564502 | 0.79 | CA12 (0.77) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4627944 | 0.79 | CA12 (0.53) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093465-A | Polyamide containing spirodilactam moieties | SHELL OIL COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| US-4940801-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4927906-A | Novel polyamideimide polymers | SHELL OIL COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4885351-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1989-12-05 | — | — | US | disclosed |