SCHEMBL7671969

SCHEMBL7671969

COC(=O)c1cccc(Cl)c1C(=O)OC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
NR4A2 P43354 3/20 0.53
LMNA P02545 4/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 4/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
ALDH1A1 P00352 3/20 0.48
CFTR P13569 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
PKM P14618 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445387 1.00 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL9637150 0.91 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL517538 0.88 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL28803912 0.87 SLC6A4 (0.50) CA12CA1CA2CA7CA9
SCHEMBL18797222 0.86 CA12 (0.47) CA12CA1CA2CA7CA9
SCHEMBL1666445 0.86 CA1 (0.64) CA12CA1CA2CA7CA9
SCHEMBL993113 0.82 TSHR (0.59) NR4A2LMNATSHRPOLBSLC6A4
SCHEMBL196555 0.82 LMNA (0.61) CA1CA2CA9NR4A2LMNA
SCHEMBL3576571 0.82 CA1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL30488606 0.82 LMNA (0.61) CA1CA2CA9NR4A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114231891-A Surface treatment process for coal mine machinery 煤炭科学研究总院 2022-03-25 CN claimed
CN-112305131-B GC-Orbitrap-MS screening and analyzing method for pesticide residues in animal derived food 中国农业科学院农业质量标准与检测技术研究所 2021-09-21 CN claimed
CN-113226036-A Compositions comprising a pyridine carboxylate herbicide and a microtubule assembly inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-06 CN claimed
CN-112305131-A GC-Orbitrap-MS screening and analyzing method for pesticide residues in animal derived food 中国农业科学院农业质量标准与检测技术研究所 2021-02-02 CN claimed
CN-111040301-A Elastic stretch film and preparation method thereof 袁水清 2020-04-21 CN claimed
CN-1215068-C Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative CHANGCHUN APPLIED CHEMISTRY (CN) 2005-08-17 CN claimed
CN-1436780-A Prepn process of 2,3,3',4'-diphenyl tetraformic dianhydride and its derivative CHANGCHUN APPLIED CHEMISTRY (CN) 2003-08-20 CN claimed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed
CN-118974024-A Substituted 2-C-azines and salts thereof and use thereof as herbicidally active substances 拜耳公司 2024-11-15 CN disclosed
CN-118974025-A Substituted 2-amino-oxazines and salts thereof and their use as herbicidal agents 拜耳公司 2024-11-15 CN disclosed
CN-118666788-A Preparation method of 2, 3',4' -biphenyl tetracarboxylic dianhydride 天津派森新材料技术有限责任公司 2024-09-20 CN disclosed
CN-112469712-B Substituted 2-heteroaryloxy pyridines and salts thereof, and their use as herbicides 拜耳公司 2024-08-13 CN disclosed
CN-113677665-B Substituted 2-heteroarylaminobenzenes and salts thereof, and their use as herbicides 拜耳公司 2024-07-16 CN disclosed
US-20020115692-A1 Tryptophan derivatives CELLTECH R&D, LTD. (GB) 2002-08-22 US disclosed
WO-2002042294-A1 1-SULFONYL SUBSTITUTED TRYPTOPHANE DERIVATIVES AND ITS USE AS INTEGRIN INHIBITORS CELLTECH R & D LIMITED (GB) 2002-05-30 WO disclosed
WO-1999050259-A2 SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS AND AROMATISATION PROCESS FOR USE THEREIN WHITE KNIGHT BIOTECHNOLOGIES LIMITED (GB) 1999-10-07 WO disclosed
EP-0405389-B1 Process for producing an aromatic compound MITSUBISHI CHEM IND (JP) 1995-01-04 EP disclosed
US-5159082-A Catalytic coupling of an aromatic sulfinic acid with an aromatic halogen compound MITSUBISHI KASEI CORPORATION (JP) 1992-10-27 US disclosed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020115692-A1 Tryptophan derivatives IDO1, TPH1, IDO2 CA12 2567/4885CA1 1136/4885CA2 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.