Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203639 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL9636999 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL2130385 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL9244937 | 0.70 | ALDH1A1 (0.39) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL9729321 | 0.69 | ALDH1A1 (0.45) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL9729328 | 0.69 | ALDH1A1 (0.45) | ALDH1A1GAAHSD17B10MAPTKMT2A | |
| SCHEMBL11837378 | 0.69 | ALDH1A1 (0.38) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL4640870 | 0.69 | — | — | |
| SCHEMBL1078049 | 0.69 | ALDH1A1 (0.57) | ALDH1A1SOAT1GAAHSD17B10MAPT | |
| SCHEMBL5741816 | 0.68 | ALDH1A1 (0.36) | ALDH1A1SOAT1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272201-B1 | STEREOSPECIFIC KETOREDUCTION OF BICYCLOOCTANEDIONE-CARBOXYLIC-ACID ESTERS BY MICROORGANISMS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-08 | — | — | EP | disclosed |
| EP-0272201-A1 | Stereospecific ketoreduction of bicyclooctanedione-carboxylic-acid esters by microorganisms | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |
| WO-1988003568-A1 | STEREOSPECIFIC KETO-REDUCTION OF BICYCLOOCTANDIONE-CARBOXYLIC ACID ESTERS BY MICROORGANISMS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-05-19 | — | — | WO | disclosed |