Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9637370

CCN(CC)c1ccc2c(c1)OC1=CC(C(C)Cl)(C(C)Cl)C=CC1=C2c1ccccc1C(=O)O.N

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ HSD17B10 Q99714 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ SLC16A3 O15427 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ SLC16A1 P53985 1/20 0.32
▸ CA12 O43570 1/20 0.31
▸ CA1 P00915 1/20 0.31
▸ CA2 P00918 1/20 0.31
▸ CA3 P07451 1/20 0.31
▸ CA4 P22748 1/20 0.31
▸ CA6 P23280 1/20 0.31
▸ CA5A P35218 1/20 0.31
▸ CA7 P43166 1/20 0.31
▸ CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15031010 0.83 SMN1; SMN2 (0.38) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL2058683 0.79 MEN1 (0.35) SMN1; SMN2MEN1KMT2AL3MBTL1HPGD
SCHEMBL3267635 0.76 MEN1 (0.41) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL27957688 0.75 SMN1; SMN2 (0.40) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL9000066 0.75 SMN1; SMN2 (0.40) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL16491631 0.75 USP2 (0.34) MEN1KMT2AL3MBTL1HSD17B10KDM4E
SCHEMBL15354850 0.75 CA12 (0.35) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL7120029 0.74 SMN1; SMN2 (0.39) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
Hydrochloric Acid SCHEMBL15720562 0.73 SMN1; SMN2 (0.36) SMN1; SMN2MEN1KMT2AL3MBTL1HSD17B10
SCHEMBL14905193 0.69 ALDH1A1 (0.31) SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 — — EP disclosed
US-4933948-A Inclusion compound of cyclodextrin and fluorescent dye EASTMAN KODAK COMPANY (US) 1990-06-12 — — US disclosed
EP-0349265-A2 Electroluminescent devices EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-03 — — EP disclosed
US-4769292-A Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (US) 1988-09-06 — — US disclosed
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