Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547886 | 0.91 | CA1 (0.50) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL19434115 | 0.88 | CA1 (0.46) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL20972363 | 0.87 | CYP1A2 (0.45) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL11700082 | 0.84 | CA1 (0.39) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL2991947 | 0.84 | CA1 (0.39) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL24287536 | 0.84 | CA1 (0.39) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL28495821 | 0.84 | CHRNB2 (0.41) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL24287742 | 0.79 | CA1 (0.35) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL2688034 | 0.78 | CYP1A2 (0.45) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL28339122 | 0.78 | CYP1A2 (0.50) | CA1CA2CA4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338946-B1 | Sweetening agents which derive from the acides l-aspartic and l-glutamotic-n-hydrocarbonés | NOFRE, Claude (FR) | 1992-07-01 | — | — | EP | claimed |
| US-4935517-A | STABILITY, INTENSITY | UNIVERSITE CLAUDE BERNARD (FR) | 1990-06-19 | — | — | US | claimed |
| EP-0338946-A1 | Sweetening agents which derive from the acides l-aspartic and l-glutamotic-n-hydrocarbonés | NOFRE, Claude (FR) | 1989-10-25 | — | — | EP | claimed |
| EP-0338946-B1 | Sweetening agents which derive from the acides l-aspartic and l-glutamotic-n-hydrocarbonés | NOFRE, Claude (FR) | 1992-07-01 | — | — | EP | disclosed |
| US-4935517-A | STABILITY, INTENSITY | UNIVERSITE CLAUDE BERNARD (FR) | 1990-06-19 | — | — | US | disclosed |
| EP-0338946-A1 | Sweetening agents which derive from the acides l-aspartic and l-glutamotic-n-hydrocarbonés | NOFRE, Claude (FR) | 1989-10-25 | — | — | EP | disclosed |