Methane

Methane

SCHEMBL9637835

C.CC1=CC(=O)NC1=O.CC1=CC(=O)NC1=O.c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.41
MAOA P21397 3/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
BLM P54132 3/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 3/20 0.41
MAOB P27338 2/20 0.41
MEN1 O00255 2/20 0.41
PLIN1 O60240 2/20 0.41
MAPK1 P28482 2/20 0.41
PLIN5 Q00G26 2/20 0.41
KMT2A Q03164 2/20 0.41
ABHD5 Q8WTS1 2/20 0.41
TP53 P04637 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL27685393 0.85 TSHR (0.43) GSK3BSMN1; SMN2MAOALMNAMAPT
Benzene SCHEMBL28483360 0.84 GSK3B (0.31) GSK3BDAO
Benzene SCHEMBL27617257 0.84 GSK3B (0.31) GSK3BDAO
SCHEMBL36967 0.84
SCHEMBL996566 0.84 GSK3A (0.33) GSK3B
Ethane SCHEMBL21589349 0.82 GSK3A (0.32) GSK3B
Hydrochloric Acid SCHEMBL5322363 0.82
Diphenylmethane SCHEMBL10593665 0.79 CALM1 (0.44) MAOALMNAMAOBMEN1KMT2A
Diphenylmethane SCHEMBL29204695 0.79 CALM1 (0.44) MAOALMNAMAOBMEN1KMT2A
Ethylbenzene SCHEMBL22749350 0.77 TP53 (0.50) SMN1; SMN2MAOALMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0251491-B1 MULTI-ELECTROLYTE TREATMENT OF CARBON FIBRES TO MODIFY SHEAR RESISTANCE AMOCO CORPORATION (US) 1992-07-01 EP disclosed
EP-0251491-A1 Multi-electrolyte treatment of carbon fibres to modify shear resistance AMOCO CORPORATION (US) 1988-01-07 EP disclosed