SCHEMBL9637890

SCHEMBL9637890

Cc1ccc(-c2cc3cc(N)ccc3oc2=O)cc1

nearest known ligand 0.83

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.83
ADORA3 P0DMS8 1/20 0.77
NPC1 O15118 1/20 0.73
MAOA P21397 3/20 0.69
PON1 P27169 1/20 0.62
ACHE P22303 1/20 0.62
NCOA1 Q15788 1/20 0.61
NCOA3 Q9Y6Q9 1/20 0.61
MIF P14174 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3277617 0.91 NPC1 (0.82) MAOBADORA3NPC1MAOAACHE
SCHEMBL14506707 0.86 MAOB (0.84) MAOBADORA3MAOAPON1MIF
SCHEMBL9079005 0.84 NPC1 (1.00) MAOBADORA3NPC1MAOAACHE
SCHEMBL13769123 0.81 MAOB (0.81) MAOBADORA3NPC1MAOAPON1
SCHEMBL14389070 0.80 MAOB (0.75) MAOBADORA3NPC1MAOAPON1
SCHEMBL12386452 0.79 MAOB (0.73) MAOBADORA3MAOAPON1MIF
SCHEMBL4992695 0.79 MAOB (0.69) MAOBADORA3NPC1MAOAACHE
SCHEMBL4983134 0.79 MAOB (0.69) MAOBADORA3NPC1MAOAACHE
SCHEMBL10144784 0.78 MAOB (0.68) MAOBADORA3NPC1MAOAPON1
SCHEMBL10024076 0.78 MIF (0.77) MAOBADORA3MAOAPON1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494231-A4 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES 1992-09-16 EP disclosed
EP-0494231-A1 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-07-15 EP disclosed
WO-1991004663-A1 6-AMINO-1,2-BENZOPYRONES USEFUL FOR TREATMENT OF VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-04-18 WO disclosed