Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 11/20 | 0.77 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.73 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAPDH | P04406 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637890 | 0.91 | MAOB (0.83) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL9079005 | 0.90 | NPC1 (1.00) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL4992695 | 0.87 | MAOB (0.69) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL4983134 | 0.87 | MAOB (0.69) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL8063336 | 0.86 | NCOA1 (0.73) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL30096432 | 0.85 | NCOA1 (1.00) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL2202460 | 0.85 | NCOA1 (1.00) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL10144784 | 0.84 | MAOB (0.68) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL3277732 | 0.78 | SMN1; SMN2 (0.63) | NPC1MAOBNCOA1NCOA3ACHE | |
| SCHEMBL8934492 | 0.78 | ESR2 (0.82) | NPC1NCOA1NCOA3MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700375-B2 | Fluorescent labeling of specific protein targets in vitro and in vivo | VALORISATION-RECHERCHE, LP (CA) | 2010-04-20 | — | — | US | disclosed |
| US-7700375-B2 | Fluorescent labeling of specific protein targets in vitro and in vivo | VALORISATION-RECHERCHE, LP (CA) | 2010-04-20 | — | — | US | disclosed |
| US-7700375-B2 | Fluorescent labeling of specific protein targets in vitro and in vivo | VALORISATION-RECHERCHE, LP (CA) | 2010-04-20 | — | — | US | disclosed |
| US-20060147948-A1 | Fluorescent labeling of specific protein targets in vitro and in vivo | UNIVERSITY OF OTTAWA (CA) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060147948-A1 | Fluorescent labeling of specific protein targets in vitro and in vivo | QPCTL, MRPL21, STAMBP | NPC1 4005/4885MAOB 3357/4885NCOA1 4412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.