Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10336617 | 1.00 | MME (0.44) | MMEFNTAFNTBACECPN1 | |
| SCHEMBL21647366 | 0.83 | MME (0.48) | MME | |
| SCHEMBL21274600 | 0.82 | MME (0.47) | MMEFNTAFNTB | |
| SCHEMBL14935643 | 0.82 | MME (0.47) | MMEFNTAFNTB | |
| SCHEMBL17100025 | 0.79 | MME (0.44) | MMEFNTAFNTB | |
| SCHEMBL9752562 | 0.79 | APAF1 (0.56) | MME | |
| SCHEMBL7620487 | 0.79 | APAF1 (0.56) | MME | |
| SCHEMBL7944349 | 0.79 | APAF1 (0.56) | MME | |
| SCHEMBL5867677 | 0.78 | MME (0.54) | MME | |
| SCHEMBL5867674 | 0.78 | MME (0.54) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137904-A | Useful in the treatment of atherosclerosis and thrombosis | G. D. SEARLE & CO. (US) | 1992-08-11 | — | — | US | disclosed |