Sulfuric Acid

Sulfuric Acid

SCHEMBL9638296

C=CCOC(=O)CC(=C)C(=O)OCC=C.O=S(=O)(O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216622 0.93 TSHR (0.43) TSHRTDP1SMN1; SMN2PKMMAPT
Phosphine SCHEMBL27976349 0.91 TSHR (0.42) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL10619756 0.84 MAPT (0.53) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL29124210 0.82 TDP1 (0.39) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL27545604 0.82 TSHR (0.46) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL7083072 0.82 GAA (0.48) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL11287787 0.81 TSHR (0.41) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL13133181 0.81 TSHR (0.41) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL29124223 0.81 TSHR (0.42) TSHRTDP1SMN1; SMN2PKMMAPT
SCHEMBL27562056 0.80 TSHR (0.36) TSHRTDP1SMN1; SMN2PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356592-B1 PROCESS FOR PRODUCING EMULSION POLYMER COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-04-01 EP disclosed
US-4973614-A ETHYLENICALLY UNSATURATED MONOMER AND WATER INSOLUBLE EPOXY RESIN DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-11-27 US disclosed
EP-0356592-A1 Process for producing emulsion polymer composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-03-07 EP disclosed