Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661739 | 0.74 | IDO1 (0.39) | MAPTHPGDTSHRHSD17B10GPR35 | |
| SCHEMBL6068003 | 0.73 | TMIGD3 (0.51) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL15274409 | 0.72 | ADORA1 (0.44) | ADORA1ADORA2ARPS6KB2MAPTMEN1 | |
| SCHEMBL18133656 | 0.72 | ERN1 (0.50) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL14027112 | 0.72 | RPS6KB2 (0.53) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL6068121 | 0.70 | TMIGD3 (0.45) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL276422 | 0.70 | MAPT (0.45) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL6067982 | 0.69 | MAPT (0.47) | ADORA1ADORA2ATMIGD3RPS6KB2ERN1 | |
| SCHEMBL29945128 | 0.69 | LTA4H (0.47) | ADORA2ARPS6KB2MAPTMEN1KMT2A | |
| SCHEMBL9927346 | 0.69 | LTA4H (0.47) | ADORA2ARPS6KB2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246114-B1 | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | GEC-MARCONI LIMITED (GB) | 1992-09-02 | — | — | EP | disclosed |
| US-4826977-A | Photochromic spiropyran compounds | THE PLESSEY COMPANY PLC (GB) | 1989-05-02 | — | — | US | disclosed |