Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276464 | 0.87 | CYP1A2 (0.56) | CYP1A2MMP2MMP12CYP3A4CYP2C9 | |
| SCHEMBL16062587 | 0.82 | HTR1B (0.45) | CYP1A2CYP1A1CYP1B1MMP2MMP12 | |
| SCHEMBL13259162 | 0.78 | KDM4E (0.51) | CYP1A2MMP2MMP12CYP3A4CYP2C9 | |
| SCHEMBL12267719 | 0.78 | NPSR1 (0.47) | CYP1A2CYP1A1CYP1B1MMP2MMP12 | |
| SCHEMBL27402182 | 0.77 | CYP1A2 (0.59) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL80946 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP1A1CYP1B1MMP2MMP12 | |
| SCHEMBL20208922 | 0.77 | CYP1A2 (0.54) | CYP1A2CYP1A1CYP1B1MMP2CYP3A4 | |
| SCHEMBL5243364 | 0.75 | NPSR1 (0.53) | CYP1A2MMP2MMP12CYP3A4CYP2C9 | |
| SCHEMBL20208683 | 0.75 | CYP1A2 (0.43) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 | |
| SCHEMBL5886608 | 0.74 | APP (0.71) | CYP1A2CYP1A1CYP1B1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098806-A | Photochromic film filter turning opaque prior to copier's light; reverts to transparent | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-03-24 | — | — | US | claimed |