Methacrylic Acid

Methacrylic Acid

SCHEMBL9638845

C1CCOC1.C=C(C)C(=O)O.C=C(C)C(=O)O.CCOC(N)=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
TSHR P16473 4/20 0.39
LMNA P02545 3/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 5/20 0.36
RECQL P46063 1/20 0.36
RAB9A P51151 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 2/20 0.34
HPGD P15428 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.33
GAA P10253 2/20 0.32
MGAM O43451 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9638711 0.91 ALOX15 (0.56) ALOX15TSHRLMNAPOLBALDH1A1
Urethane SCHEMBL7059731 0.88 ALOX15 (0.65) ALOX15TSHRLMNAPOLBALDH1A1
Methacrylic Acid SCHEMBL29579615 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL2062627 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL29580156 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL31087603 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL403852 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL9903977 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL900407 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT
Methacrylic Acid SCHEMBL709886 0.86 ALOX15 (0.68) ALOX15TSHRLMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147923-A Water-swellable random copolymers of N, N-dimethylacrylamide and (cyclo)aliphatic or aromatic acrylic esters having low cloud points CIBA-GEIGY CORPORATION (US) 1992-09-15 US disclosed
US-5104954-A Swellable random copolymers of N,N-dimethylacrylamide and acrylic esters having reversible cloud points; for heat activated sunscreens CIBA-GEIGY CORPORATION (US) 1992-04-14 US disclosed