Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.71 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.71 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.71 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.71 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.71 |
| ▸ | APP | P05067 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | SLC7A11 | Q9UPY5 | 5/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495322 | 0.87 | SENP2 (0.77) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL9640919 | 0.84 | APP (0.81) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL9639508 | 0.84 | APP (0.81) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL15120241 | 0.83 | SENP2 (0.71) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL16153272 | 0.83 | SENP2 (1.00) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL15120244 | 0.83 | SENP2 (0.71) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL15120253 | 0.83 | SENP2 (0.71) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL18044218 | 0.83 | SENP2 (0.71) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL29473542 | 0.83 | SENP2 (1.00) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL13868280 | 0.83 | SENP2 (1.00) | SENP2SENP1SUMO2SUMO1SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287909-B1 | AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR | SALUTAR, INC. (US) | 1992-09-02 | — | — | EP | disclosed |