SCHEMBL9639461

SCHEMBL9639461

C=CC(=O)OCS(=O)(=O)O.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.46
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
THRB P10828 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483800 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27821844 0.95 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Methane SCHEMBL8401172 0.95 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene Glycol SCHEMBL27952389 0.91 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Benzene SCHEMBL28022550 0.91 THRB (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6916022 0.86 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Di(Hydroxyethyl)Ether SCHEMBL27940526 0.85 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
Biphenyl SCHEMBL27622834 0.82 THRB (0.49) TSHRALDH1A1TP53HIF1ACYP3A4
Thioglycolic Acid SCHEMBL27952397 0.82 TSHR (0.44) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27952414 0.79 TSHR (0.67) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227358-B1 HOUSING PACK FOR PHOTOGRAPHIC PROCESSING SOLUTION KONICA CORPORATION (JP) 1992-08-12 EP disclosed
US-5015560-A Purification of photographic solutions bu absorption on a resin KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-05-14 US disclosed
EP-0201186-B1 METHOD OF TREATING PHOTOGRAPHIC WASTE SOLUTIONS AND AUTOMATIC PHOTOGRAPH PROCESSOR KONICA CORPORATION (JP) 1990-05-30 EP disclosed
US-4791013-A STORAGE AND WASTE COMPARTMENTS; OXYGEN BARRIER MEMBRANE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-12-13 US disclosed
EP-0227358-A2 Housing pack for photographic processing solution KONICA CORPORATION (JP) 1987-07-01 EP disclosed
EP-0201186-A1 Method of treating photographic waste solutions and automatic photograph processor KONICA CORPORATION (JP) 1986-11-12 EP disclosed
US-4480025-A Water reservoir layers in bleach-fix sheets EASTMAN KODAK COMPANY (US) 1984-10-30 US disclosed
EP-0117165-A2 Bleach-fix sheet EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-08-29 EP disclosed