Oxirane

Oxirane

SCHEMBL9640207

C1CO1.C=C(CO)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
OR51E2 Q9H255 1/20 0.35
HSD17B10 Q99714 2/20 0.34
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28288199 0.88 ALDH1A1 (0.36) TET2TET3TET1OR51E2HSD17B10
SCHEMBL136796 0.86
SCHEMBL8935074 0.83
Water SCHEMBL26128700 0.83 OR51E2 (0.42) TET2TET3TET1OR51E2HSD17B10
SCHEMBL11785793 0.83
SCHEMBL15010320 0.83
Ammonia Solution, Strong SCHEMBL11784573 0.83
SCHEMBL9638925 0.79 TET2 (0.36) TET2TET3TET1OR51E2HSD17B10
Aziridine SCHEMBL5828789 0.79 TET2 (0.36) TET2TET3TET1OR51E2HSD17B10
Oxirane SCHEMBL17997376 0.77 TET2 (0.37) TET2TET3TET1HSD17B10GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231002-B1 CROSSLINKABLE SOLID RUBBERY POLYMERS BASF Aktiengesellschaft (DE) 1992-08-12 EP disclosed
US-4762892-A ETHYLENE-ACRYLIC OR METHACRYLIC ACID-ALKYL ACRYLATE MODIFIED TO CONTAIN UNSATURATED SIDE CHAINS BASF AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
EP-0231002-A2 Crosslinkable solid rubbery polymers BASF Aktiengesellschaft (DE) 1987-08-05 EP disclosed