⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177849 | 1.00 | — | — | |
| SCHEMBL9641013 | 1.00 | — | — | |
| SCHEMBL8153060 | 0.78 | TDP1 (0.32) | — | |
| SCHEMBL454918 | 0.75 | — | — | |
| SCHEMBL4442753 | 0.75 | — | — | |
| SCHEMBL9635466 | 0.73 | — | — | |
| SCHEMBL1286839 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL2476307 | 0.73 | — | — | |
| Potassium Ion SCHEMBL11581788 | 0.73 | — | — | |
| SCHEMBL4465736 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287042-B1 | 2-SULPHINYL-ACETYL-1,3-THIAZOLIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-16 | — | — | EP | disclosed |
| US-4849437-A | 2-sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-07-18 | — | — | US | disclosed |
| EP-0287042-A1 | 2-Sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-10-19 | — | — | EP | disclosed |