SCHEMBL9640337

SCHEMBL9640337

O=C(c1cc(O)c(O)c(O)c1)c1cc(Cl)c(O)c(O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.56
KDM4E B2RXH2 4/20 0.43
LMNA P02545 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
FUT7 Q11130 2/20 0.43
TP53 P04637 2/20 0.43
HPGD P15428 2/20 0.43
MAPK1 P28482 2/20 0.43
HSD17B10 Q99714 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
FUT4 P22083 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9638961 0.84 HDAC1 (0.70) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL19003431 0.78 HDAC1 (0.58) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL9639923 0.77 HDAC1 (0.56) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL9639963 0.77 HDAC1 (0.56) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL9639016 0.77 HDAC1 (0.56) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL27319286 0.76 HDAC1 (0.55) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL7551865 0.76 HDAC1 (0.59) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL9639868 0.74 CA12 (0.41) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL21935566 0.74 HDAC1 (0.62) HDAC1KDM4ELMNATDP1ALDH1A1
SCHEMBL352369 0.73 KDM4E (0.65) HDAC1KDM4ELMNATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227487-B1 POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-07-15 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed