Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260774 | 1.00 | TSHR (0.44) | TSHRDNM1LSSNAAAHCAR2 | |
| SCHEMBL9871522 | 0.95 | DNM1 (0.38) | TSHRDNM1LSSHCAR2THRB | |
| SCHEMBL11137264 | 0.91 | DNM1 (0.52) | TSHRDNM1LSSTHRBTHRA | |
| SCHEMBL3185601 | 0.87 | DNM1 (0.34) | TSHRDNM1LSSNAAAHCAR2 | |
| SCHEMBL16178720 | 0.86 | TSHR (0.41) | TSHRNAAAHCAR2APEX1NPSR1 | |
| SCHEMBL7785353 | 0.83 | TSHR (0.56) | TSHRDNM1LSSNAAATHRB | |
| SCHEMBL8349322 | 0.83 | TSHR (0.56) | TSHRDNM1LSSNAAATHRB | |
| SCHEMBL15772796 | 0.82 | DNM1 (0.42) | TSHRDNM1APEX1 | |
| Bromide SCHEMBL7779909 | 0.82 | TSHR (0.54) | TSHRDNM1LSSNAAATHRB | |
| SCHEMBL1403008 | 0.80 | KDM4A (0.33) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382493-B1 | BRANCHED POLYMERS AS FUEL OIL ADDITIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-09 | — | — | EP | disclosed |