Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7358505 | 0.90 | LMNA (0.52) | LMNAPPIDNPC1NOS2RAB9A | |
| SCHEMBL25083223 | 0.83 | GAA (0.53) | LMNANPC1RAB9AKDM4EGAA | |
| SCHEMBL1120663 | 0.79 | LMNA (0.54) | LMNAPPIDNPC1NOS2RAB9A | |
| SCHEMBL1602631 | 0.79 | TOP2A (0.56) | LMNANPC1NOS2RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL15562708 | 0.78 | TOP2A (0.54) | LMNANPC1NOS2RAB9AKDM4E | |
| SCHEMBL7748124 | 0.77 | GAA (0.50) | NPC1RAB9AGAAALDH1A1HTT | |
| SCHEMBL9045499 | 0.77 | GAA (0.68) | LMNANPC1NOS2RAB9AKDM4E | |
| SCHEMBL11954569 | 0.77 | TOP2A (0.57) | LMNANPC1NOS2RAB9AALDH1A1 | |
| SCHEMBL7436411 | 0.76 | GAA (0.51) | ALOX15LMNANPC1RAB9AKDM4E | |
| SCHEMBL22338218 | 0.76 | GAA (0.56) | NPC1RAB9AGAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240914-B1 | PEPTIDE DERIVATIVES AND ACTIVITY MEASURING METHOD OF PHYSIOLOGICALLY ACTIVE SUBSTANCES USING THE SAME AS SUBSTRATES | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-19 | — | — | EP | claimed |
| US-5120644-A | Reacting enzyme with substrate containing fluorescent substituent | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | claimed |