Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640501 | 1.00 | KMT2A (0.44) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639756 | 0.86 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9640735 | 0.86 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9640709 | 0.86 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639769 | 0.86 | MEN1 (0.45) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639346 | 0.85 | MEN1 (0.51) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639365 | 0.85 | MEN1 (0.51) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639638 | 0.84 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9639660 | 0.84 | KMT2A (0.56) | KMT2AMEN1ALDH1A1HSD17B10MAPT | |
| SCHEMBL9640627 | 0.79 | CYP1A2 (0.43) | KMT2AMEN1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287909-B1 | AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR | SALUTAR, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5008099-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |