Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739299 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL6771895 | 0.90 | HTR2A (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL10363296 | 0.89 | MAOB (0.42) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL10371377 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9519940 | 0.85 | TDP1 (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL8690166 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL8923130 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9519038 | 0.85 | TDP1 (0.40) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL10861535 | 0.85 | TDP1 (0.44) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL10390151 | 0.85 | TDP1 (0.44) | ALDH1A1MAPTHPGDTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |