Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL29356227 | 0.75 | TDP1 (1.00) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL220 | 0.75 | TDP1 (1.00) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL380499 | 0.75 | TDP1 (1.00) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Biphenyl SCHEMBL10770860 | 0.74 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRMAPK1CYP1A2 | |
| Phthalic Anhydride SCHEMBL28897882 | 0.73 | TDP1 (0.82) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL18038400 | 0.72 | TDP1 (0.93) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL1871448 | 0.72 | TDP1 (0.93) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL21824259 | 0.72 | TDP1 (0.93) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL21874610 | 0.72 | TDP1 (0.93) | TDP1ALOX15ALDH1A1TSHRMAPK1 | |
| Phthalic Anhydride SCHEMBL6302828 | 0.72 | TDP1 (0.93) | TDP1ALOX15ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281825-B1 | SILICONE POLYIMIDES AND METHOD FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 1992-09-09 | — | — | EP | claimed |
| US-4826916-A | PROTECTIVE COATINGS | GENERAL ELECTRIC COMPANY (US) | 1989-05-02 | — | — | US | claimed |
| EP-0281825-A2 | Silicone polyimides and method for making | GENERAL ELECTRIC COMPANY (US) | 1988-09-14 | — | — | EP | claimed |