Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9640898 | 0.99 | DRD3 (0.43) | DRD3HTR2BCHRM2HTR1AMDM2 | |
| SCHEMBL2295365 | 0.83 | DRD3 (0.47) | DRD3HTR2BCHRM2HTR1ARIPK1 | |
| SCHEMBL2296807 | 0.83 | DRD3 (0.47) | DRD3HTR2BCHRM2HTR1ARIPK1 | |
| SCHEMBL17166237 | 0.83 | DRD3 (0.64) | DRD3HTR2BCHRM2HTR1A | |
| SCHEMBL9640702 | 0.83 | CNR2 (0.43) | DRD3HTR2BCHRM2HTR1ACNR2 | |
| SCHEMBL2293475 | 0.82 | PDE10A (0.42) | DRD3CNR2 | |
| SCHEMBL2298189 | 0.82 | PDE10A (0.42) | DRD3CNR2 | |
| SCHEMBL13093625 | 0.82 | CNR2 (0.45) | DRD3HTR2BCHRM2HTR1ACNR2 | |
| SCHEMBL12363949 | 0.82 | CNR2 (0.45) | DRD3HTR2BCHRM2HTR1ACNR2 | |
| SCHEMBL9641992 | 0.82 | CNR2 (0.45) | DRD3HTR2BCHRM2HTR1ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290122-B1 | MORPHOLINE DERIVATIVES AND THEIR USE | BEECHAM GROUP PLC (GB) | 1992-12-23 | — | — | EP | claimed |
| US-5082840-A | Animal growth regulators | BEECHAM GROUP P.L.C. (GB) | 1992-01-21 | — | — | US | claimed |
| EP-0290122-A1 | Morpholine derivatives and their use | BEECHAM GROUP PLC (GB) | 1988-11-09 | — | — | EP | claimed |