Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9678921 | 0.99 | CNR2 (0.42) | CNR2DRD3CCR5CHRM2HTR1A | |
| SCHEMBL9640630 | 0.83 | DRD3 (0.44) | CNR2DRD3CHRM2HTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL9640898 | 0.82 | DRD3 (0.43) | CNR2DRD3CHRM2HTR1AHTR2B | |
| SCHEMBL9640392 | 0.78 | MDM2 (0.42) | CCR5 | |
| SCHEMBL9641992 | 0.72 | CNR2 (0.45) | CNR2DRD3CHRM2HTR1AHTR2B | |
| SCHEMBL13093625 | 0.72 | CNR2 (0.45) | CNR2DRD3CHRM2HTR1AHTR2B | |
| SCHEMBL12363949 | 0.72 | CNR2 (0.45) | CNR2DRD3CHRM2HTR1AHTR2B | |
| SCHEMBL18997540 | 0.71 | RIPK1 (0.48) | DRD3CHRM2HTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL9641424 | 0.70 | CNR2 (0.44) | CNR2DRD3CHRM2HTR1AHTR2B | |
| Hydrochloric Acid SCHEMBL9641578 | 0.69 | DRD3 (0.65) | CNR2DRD3CHRM2HTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290122-B1 | MORPHOLINE DERIVATIVES AND THEIR USE | BEECHAM GROUP PLC (GB) | 1992-12-23 | — | — | EP | claimed |
| US-5082840-A | Animal growth regulators | BEECHAM GROUP P.L.C. (GB) | 1992-01-21 | — | — | US | claimed |
| EP-0290122-A1 | Morpholine derivatives and their use | BEECHAM GROUP PLC (GB) | 1988-11-09 | — | — | EP | claimed |