Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 9/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 8/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 6/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 6/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 6/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640627 | 1.00 | CYP1A2 (0.43) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9639365 | 0.88 | MEN1 (0.51) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9639346 | 0.88 | MEN1 (0.51) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9640088 | 0.81 | CYP1A2 (0.56) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9640108 | 0.81 | CYP1A2 (0.56) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9639769 | 0.80 | MEN1 (0.45) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9640735 | 0.80 | ALDH1A1 (0.61) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9639756 | 0.80 | MEN1 (0.45) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9640709 | 0.80 | ALDH1A1 (0.61) | CYP1A2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL9640501 | 0.79 | KMT2A (0.44) | CYP1A2SENP2SENP1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287909-B1 | AMYLOIDOSIS AND ALZHEIMER'S DISEASE DIAGNOSTIC ASSAY AND REAGENTS THEREFOR | SALUTAR, INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5039511-A | Amyloidosis and alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-08-13 | — | — | US | disclosed |
| US-5008099-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4933156-A | Amyloidosis and Alzheimer's disease diagnostic assay and reagents therefor | SALUTAR, INC. (US) | 1990-06-12 | — | — | US | disclosed |