Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 16/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9640798 | 0.99 | CYP11B1 (0.53) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL10583555 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL9640779 | 0.86 | CYP11B1 (0.47) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| Hydrochloric Acid SCHEMBL9640790 | 0.85 | CYP11B1 (0.46) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL10583558 | 0.83 | CYP11B1 (0.45) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL10791218 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL10795658 | 0.77 | CYP11B1 (0.48) | CYP11B1CYP11B2 | |
| SCHEMBL9641848 | 0.76 | CYP11B1 (0.54) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 | |
| SCHEMBL2200112 | 0.75 | CYP11B1 (0.56) | CYP11B1CYP11B2IDO1P2RX7HPGDS | |
| SCHEMBL9125325 | 0.75 | CYP11B1 (0.42) | CYP11B1CYP11B2IDO1P2RX7HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311447-B1 | AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1992-08-26 | — | — | EP | claimed |
| EP-0311447-B1 | AROMATASE INHIBITING 4(5)-IMIDAZOLES | ORION-YHTYMÀ OY (FI) | 1992-08-26 | — | — | EP | disclosed |
| US-5098923-A | Antiestrogens, anticarcinogenic agents or fungicides | FARMOS-YHTYMA OY (FI) | 1992-03-24 | — | — | US | disclosed |
| EP-0311447-A1 | Aromatase inhibiting 4(5)-imidazoles | ORION-YHTYMÀ OY (FI) | 1989-04-12 | — | — | EP | disclosed |