Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 18/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 18/20 | 0.48 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797165 | 0.87 | CYP11B1 (0.44) | CYP11B1CYP11B2FNTAFNTBLMNA | |
| SCHEMBL10794751 | 0.81 | KCNH2 (0.40) | CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL3822319 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL10792230 | 0.78 | FNTA (0.43) | CYP11B1CYP11B2FNTAFNTBLMNA | |
| SCHEMBL3822189 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL10791218 | 0.77 | CYP11B1 (0.54) | CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL3820773 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 | |
| SCHEMBL9640783 | 0.77 | CYP11B1 (0.54) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9640798 | 0.76 | CYP11B1 (0.53) | CYP11B1CYP11B2FNTAFNTB | |
| SCHEMBL6929093 | 0.76 | CYP11B1 (0.66) | CYP11B1CYP11B2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE32400-E | Substituted imidazole derivatives and their use as anti-thrombosis agents | FARMOS YHTYMA OY (FI) | 1987-04-14 | — | — | US | disclosed |
| US-4514412-A | HYPOTENSIVES, BETA BLOCKERS | FARMOS YHTYMA OY (FI) | 1985-04-30 | — | — | US | disclosed |
| EP-0058047-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos-Yhtyma Oy (FI) | 1984-11-07 | — | — | EP | disclosed |