Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640734 | 0.91 | KDM4E (0.37) | TSHRKDM4EKMT2AMAPK1TDP1 | |
| SCHEMBL9640527 | 0.91 | TSHR (0.36) | TSHRKCNA5KDM4EKMT2AATM | |
| SCHEMBL98701 | 0.91 | TSHR (0.40) | TSHRKCNA5KDM4EKMT2AATM | |
| SCHEMBL9640755 | 0.89 | DNM1 (0.36) | KDM4EMAPK1TDP1 | |
| SCHEMBL436610 | 0.88 | KDM4E (0.36) | TSHRKDM4EKMT2AATMTDP1 | |
| SCHEMBL9641282 | 0.87 | DNM1 (0.39) | — | |
| SCHEMBL9641784 | 0.87 | DNM1 (0.39) | — | |
| SCHEMBL9641806 | 0.87 | DNM1 (0.39) | — | |
| SCHEMBL10989513 | 0.87 | DNM1 (0.39) | — | |
| SCHEMBL9640548 | 0.87 | DNM1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128408-A | Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1992-07-07 | — | — | US | disclosed |