Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732081 | 0.89 | TP53 (0.54) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL28957247 | 0.82 | TP53 (0.44) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL9896547 | 0.80 | TP53 (0.54) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL12879212 | 0.80 | TP53 (0.54) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL11890361 | 0.78 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL11890360 | 0.78 | TP53 (0.50) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL8390073 | 0.78 | TP53 (0.47) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL26986871 | 0.76 | TP53 (0.43) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL14006052 | 0.72 | CTSK (0.37) | KDM4E | |
| SCHEMBL9579830 | 0.72 | TP53 (0.40) | TP53KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098929-A | Insecticides, insect attractants, fungicides or oxidase inhibitors | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |