Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642215 | 0.82 | PTGS1 (0.38) | PTGS1PTGS2ALOX5NPC1GAA | |
| SCHEMBL9642269 | 0.78 | PTGS1 (0.44) | PTGS1PTGS2ALOX5KDM4ENPC1 | |
| SCHEMBL17705386 | 0.76 | PTGS1 (0.51) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL9640961 | 0.74 | PTGS1 (0.50) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL28667713 | 0.72 | IDO1 (0.35) | PTGER4PTGER3PTGER2KDM4EMAPT | |
| SCHEMBL14013661 | 0.71 | ALOX5 (0.41) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL7294523 | 0.71 | ALOX5 (0.42) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL9731627 | 0.71 | ALOX5 (0.46) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL3726729 | 0.71 | ALOX5 (0.46) | PTGS1PTGS2ALOX5NISCHKDM4E | |
| SCHEMBL30529006 | 0.71 | ALOX5 (0.46) | PTGS1PTGS2ALOX5NISCHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338895-B1 | HETEROAROTINOID DERIVATIVES, THEIR PROCESSES OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR (FR) | 1992-09-23 | — | — | EP | claimed |