SCHEMBL9640968

SCHEMBL9640968

CCCC(CN)c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
SLC6A4 P31645 1/20 0.43
AOC3 Q16853 1/20 0.42
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
CASR P41180 1/20 0.38
NR2E1 Q9Y466 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1379349 0.89 ALDH1A1 (0.50) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL9819778 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2126036 0.86 ALDH1A1 (0.47) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL7384530 0.83 CYP2C9 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL1061264 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL7384532 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL2127289 0.83 ALDH1A1 (0.44) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL7385975 0.81 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL19003694 0.81 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4
SCHEMBL16594678 0.81 ALDH1A1 (0.43) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023237729-A1 PROCESS FOR MAKING A SUBSTANTIALLY NITROSAMINE-FREE, SUBSTANTIALLY PEROXIDE-FREE, SUBSTANTIALLY COLORLESS AMINE OXIDE BASF SE (DE) 2023-12-14 WO disclosed
EP-0320694-B1 AMINE OXIDE PROCESS ETHYL CORPORATION (US) 1992-09-16 EP disclosed
EP-0424965-A1 Amine oxide process ETHYL CORPORATION (US) 1991-05-02 EP disclosed
US-4994614-A Reacting tertiary amines with aqueous hydrogen peroxide in presence of synergistic combination of ascorbic acid and carbon dioxide; purity ETHYL CORPORATION (US) 1991-02-19 US disclosed
US-4960934-A Amine oxide process ETHYL CORPORATION (US) 1990-10-02 US disclosed
US-4942260-A REACTION OF A TERT-AMINE WITH HYDROGEN PEROXIDE IN THE PRESENCE OF CATALYTIC CARBON DIOXIDE ETHYL CORPORATION (US) 1990-07-17 US disclosed
EP-0356918-A1 Amine oxide process ETHYL CORPORATION (US) 1990-03-07 EP disclosed
US-4889954-A DIALKYLCARBONATE CATALYST ETHYL CORPORATION (US) 1989-12-26 US disclosed
EP-0307184-A2 Preparation of Amine Oxides ETHYL CORPORATION (US) 1989-03-15 EP disclosed