Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10595784 | 1.00 | POLB (0.56) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5345594 | 0.98 | POLB (0.56) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31662033 | 0.90 | MEN1 (0.60) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6907072 | 0.88 | POLB (0.52) | POLBSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4316835 | 0.88 | HRH3 (0.53) | POLB | |
| SCHEMBL7140249 | 0.86 | PREP (0.46) | PREPSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8880304 | 0.85 | POLB (0.49) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8880296 | 0.85 | POLB (0.49) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL29878 | 0.85 | POLB (0.62) | POLBPREPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL71528 | 0.85 | POLB (0.62) | POLBPREPSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| US-4810721-A | ANTIAMNESIA | SUNTORY LIMITED (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |