Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643097 | 1.00 | ABCB11 (0.54) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9642059 | 0.92 | ABCB11 (0.63) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9641994 | 0.92 | ABCB11 (0.63) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9643010 | 0.91 | ABCB11 (0.65) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9642724 | 0.85 | ABCB11 (0.58) | ABCB11ALDH1A1TDP1L3MBTL1PSEN1 | |
| SCHEMBL9643195 | 0.85 | ABCB11 (0.58) | ABCB11ALDH1A1TDP1L3MBTL1PSEN1 | |
| SCHEMBL9643666 | 0.84 | ABCB11 (0.67) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9641821 | 0.84 | ABCB11 (0.54) | ABCB11ALDH1A1PTGER1DHODH | |
| SCHEMBL9643094 | 0.84 | ABCB11 (0.54) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL9642397 | 0.84 | ABCB11 (0.54) | ABCB11ALDH1A1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |